Serum and Peritoneal Fluid CA 125 Levels Infertile Women with Pelvic Endometriosis in Urummia

Authors

  • Farokh Ghavam From the Departments of Pathobiology, Obstetrics and Gynecology and Statistics, Urumia University of Medical Sciences,Iran.
  • Lida Rafieyee From the Departments of Pathobiology, Obstetrics and Gynecology and Statistics, Urumia University of Medical Sciences,Iran.
  • Mohammad hossein Ansari From the Departments of Pathobiology, Obstetrics and Gynecology and Statistics, Urumia University of Medical Sciences,Iran.
  • Shaker Salari From the Departments of Pathobiology, Obstetrics and Gynecology and Statistics, Urumia University of Medical Sciences,Iran.
Abstract:

SUMMARY Infertility has a special importance in gynecology in causing social, psychological and somatic prohlems. Endometriosis is a benign but progressive disorder in reproductive life and is more common in infertile women. CA 125 is a cell membrane glycoprotein. The endometrium is one the known source of this antigen and seems to be elevated in the pelvic endometriosis. In this study, from 168 infertile women that videolaparoscopy were undertaken, 27 found to have Endometriosis. Serum and peritoneal fluid level of CA 125 were determined in these patients and control groups by RIA and EIA. Serum levels of CA 125 were within normal limits in patients and control groups. But peritoneal fluid level of CA125 in patients with Endometriosis showed markedly higher than control groups. No relation is noted between peritoneal level of CAl25 and stages of endometriosis. This study emphasizes that the peritoneal fluid levels of CA 125 is more sensitive than the serum levels and can be noted in pelvic endometriosis as a diagnostic tool.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Positive correlation between serum and peritoneal fluid CA-125 levels in women with pelvic endometriosis.

CONTEXT AND OBJECTIVE One of the diagnostic markers of endometriosis is CA-125, and elevated levels of this are caused by high concentrations in the ectopic endometrium. The objective of this study was to correlate CA-125 levels in serum and peritoneal fluid from women with and without pelvic endometriosis. DESIGN AND SETTING This was a prospective, cross-sectional, controlled study of consec...

full text

The Correlation between Serum and Peritoneal Fluid CA125 Level in Women with Pelvic Endometriosis

Background Despite a high prevalence of endometriosis, there still exist many challenges in diagnosing the disease. This study aims to evaluate non-invasive and practical diagnostic methods by measuring serum and peritoneal fluid CA 125 levels in patients with endometriosis. A secondary aim is to determine the correlation between these markers with the stage of disease as well as the relationsh...

full text

Serum and Peritoneal Fluid Cytokine Profiles in Infertile Women with Endometriosis

Background: Endometriosis is a chronic inflammatory disease with the growth of endometrial cells out of uterus and in the peritoneal cavity. T cell subsets participate in the establishment and progress of the disease by producing different cytokines. Objective: To investigate a group of cytokines related to Th1/Th2/Th17/Treg subsets within both peripheral blood...

full text

CA-125 concentration in serum and peritoneal fluid in patients with endometriosis – preliminary results

INTRODUCTION Cancer antigen 125 (CA-125), known as a biomarker for women genital tract malignancies, could be also useful in detecting and monitoring endometriosis. The aim of this study was to evaluate CA-125 in serum and peritoneal fluid (PF) as an indicator of endometriosis. MATERIAL AND METHODS Fifty-six patients admitted to the First Department of Obstetrics and Gynaecology for diagnosti...

full text

Pelvic-peritoneal tuberculosis with elevated serum and peritoneal fluid Ca-125 levels. A report of two cases.

We report 2 patients with pelvic-peritoneal tuberculosis and elevated serum and peritoneal fluid levels of Ca-125. The first was a young and infertile women who had cul-de-sac nodularity and dysmenorrhea. The other was postmenopausal and presented with weight loss and ascites. While a preoperative diagnosis of endometriosis was made in the former, intraperitoneal malignancy was considered in th...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 21  issue 1

pages  40- 47

publication date 1997-03

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023